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1

Stereochemical Determination of the Leupyrrins and Total Synthesis of Leupyrrin A 1

Herkommer, Daniel, Thiede, Sebastian, Wosniok, Paul R., Dreisigacker, Sandra, Tian, Maoqun, Debnar, Thomas, Irschik, Herbert, Menche, Dirk

Journal:

Journal of the American Chemical Society

Year:

2015

Language:

english

File:

PDF, 853 KB

english, 2015

2

A fluorescence anisotropy assay to discover and characterize ligands targeting the maytansine site of tubulin

Menchon, Grégory, Prota, Andrea E., Lucena-Agell, Daniel, Bucher, Pascal, Jansen, Rolf, Irschik, Herbert, Müller, Rolf, Paterson, Ian, Díaz, J. Fernando, Altmann, Karl-Heinz, Steinmetz, Michel O.

Journal:

Nature Communications

Year:

2018

Language:

english

File:

PDF, 1.21 MB

english, 2018

3

Maracin und Maracen: neuartige Ethinylvinylether- bzw. α-Chlordivinylether-Antibiotica aus Sorangium cellulosum mit spezifischer Wirkung gegen Mycobakterien

Martina Herrmann, Bettina Böhlendorf, Herbert Irschik, Hans Reichenbach, Gerhard Höfle

Journal:

Angewandte Chemie

Year:

1998

Language:

german

File:

PDF, 87 KB

german, 1998

4

Maracin and Maracen: New Types of Ethynyl Vinyl Ether and α-Chloro Divinyl Ether Antibiotics from Sorangium cellulosum with Specific Activity Against Mycobacteria

Martina Herrmann, Bettina Böhlendorf, Herbert Irschik, Hans Reichenbach, Gerhard Höfle

Journal:

Angewandte Chemie International Edition

Year:

1998

Language:

english

File:

PDF, 87 KB

english, 1998

5

Komplexe Biosynthese in Myxobakterien: Bildung der Leupyrrine in Sorangiumcellulosum

Helge Björn Bode, Silke C. Wenzel, Herbert Irschik, Gerhard Höfle, Rolf Müller

Journal:

Angewandte Chemie

Year:

2004

Language:

german

File:

PDF, 207 KB

german, 2004

6

Unusual Biosynthesis of Leupyrrins in the Myxobacterium Sorangium cellulosum

Helge Björn Bode, Silke C. Wenzel, Herbert Irschik, Gerhard Höfle, Rolf Müller

Journal:

Angewandte Chemie International Edition

Year:

2004

Language:

english

File:

PDF, 205 KB

english, 2004

7

Isolation and Total Synthesis of Icumazoles and Noricumazoles—Antifungal Antibiotics and Cation-Channel Blockers from Sorangium cellulosum

Jenny Barbier, Dr. Rolf Jansen, Dr. Herbert Irschik, Dr. Stefan Benson, Dr. Klaus Gerth, Bettina Böhlendorf, Prof. Dr. Gerhard Höfle, Prof. Dr. Hans Reichenbach, Jens Wegner, Dr. Carsten Zeilinger, Pr

Journal:

Angewandte Chemie International Edition

Year:

2012

Language:

english

File:

PDF, 429 KB

english, 2012

8

Production of the Tubulin Destabilizer Disorazol in Sorangium cellulosum: Biosynthetic Machinery and Regulatory Genes

Maren Kopp, Herbert Irschik, Silke Pradella, Rolf Müller

Journal:

Year:

2005

Language:

english

File:

PDF, 414 KB

english, 2005

9

SorF: A Glycosyltransferase With Promiscuous Donor Substrate Specificity in vitro

Maren Kopp, Carsten Rupprath, Herbert Irschik, Andreas Bechthold, Lothar Elling, Rolf Müller

Journal:

Year:

2007

Language:

english

File:

PDF, 182 KB

english, 2007

10

Chivosazoles A and F, Cytostatic Macrolides from Myxobacteria, Interfere with Actin

Randi Diestel, Herbert Irschik, Rolf Jansen, Mohammed W. Khalil , Hans Reichenbach, Florenz Sasse

Journal:

Year:

2009

Language:

english

File:

PDF, 516 KB

english, 2009

11

Analysis of the Sorangicin Gene Cluster Reinforces the Utility of a Combined Phylogenetic/Retrobiosynthetic Analysis for Deciphering Natural Product Assembly by trans-AT PKS

Herbert Irschik , Maren Kopp , Kira J. Weissman, Kathrin Buntin, Jörn Piel, Rolf Müller

Journal:

Year:

2010

Language:

english

File:

PDF, 633 KB

english, 2010

12

Thuggacins, Macrolide Antibiotics Active against Mycobacterium tuberculosis: Isolation from Myxobacteria, Structure Elucidation, Conformation Analysis and Biosynthesis

Heinrich Steinmetz, Herbert Irschik, Brigitte Kunze, Hans Reichenbach, Gerhard Höfle, Rolf Jansen

Journal:

Chemistry - A European Journal

Year:

2007

Language:

english

File:

PDF, 229 KB

english, 2007

13

Antibiotics from Gliding Bacteria. Part 97. Tuscolid (I) and Tuscoron A (II) and B (III): Isolation, Structural Elucidation and Studies on the Biosynthesis of Novel Furan-3(2H)-one-Containing Metabolites from the Myxobacterium Sorangium cellulosum.

Jutta Niggemann, Martina Herrmann, Klaus Gerth, Herbert Irschik, Hans Reichenbach, Gerhard Hoefle

Journal:

Year:

2004

File:

PDF, 85 KB

2004

14

ChemInform Abstract: Carolacton — A Macrolide Ketocarbonic Acid that Reduces Biofilm Formation by the Caries- and Endocarditis-Associated Bacterium Streptococcus mutans.

Rolf Jansen, Herbert Irschik, Volker Huch, Dietmar Schummer, Heinrich Steinmetz, Martin Bock, Thomas Schmidt, Andreas Kirschning, Rolf Mueller

Journal:

Year:

2010

File:

PDF, 19 KB

2010

15

ChemInform Abstract: Isolation and Synthesis of Chivotriene (I), a Chivosazole Shunt Product from Sorangium cellulosum.

Tobias Brodmann, Dominic Janssen, Florenz Sasse, Herbert Irschik, Rolf Jansen, Rolf Mueller, Markus Kalesse

Journal:

Year:

2011

File:

PDF, 23 KB

2011

16

Tuscolid and Tuscoron A and B: Isolation, Structural Elucidation and Studies on the Biosynthesis of Novel Furan-3(2H)-one-Containing Metabolites from the Myxobacterium Sorangium Cellulosum

Jutta Niggemann, Martina Herrmann, Klaus Gerth, Herbert Irschik, Hans Reichenbach, Gerhard Höfle

Journal:

European Journal of Organic Chemistry

Year:

2004

Language:

english

File:

PDF, 143 KB

english, 2004

17

Carolacton – A Macrolide Ketocarbonic Acid that Reduces Biofilm Formation by the Caries- and Endocarditis-Associated Bacterium Streptococcus mutans

Rolf Jansen, Herbert Irschik, Volker Huch, Dietmar Schummer, Heinrich Steinmetz, Martin Bock, Thomas Schmidt, Andreas Kirschning, Rolf Müller

Journal:

European Journal of Organic Chemistry

Year:

2010

Language:

english

File:

PDF, 255 KB

english, 2010

18

Isolation and Synthesis of Chivotriene, a Chivosazole Shunt Product from Sorangium cellulosum

Tobias Brodmann, Dominic Janssen, Florenz Sasse, Herbert Irschik, Rolf Jansen, Rolf Müller, Markus Kalesse

Journal:

European Journal of Organic Chemistry

Year:

2010

Language:

english

File:

PDF, 361 KB

english, 2010

19

Antibiotika aus Gleitenden Bakterien, XVII. Myxopyronin A und B – zwei neue Antibiotika aus Myxococcus fulvus Stamm Mx f50

Werner Kohl, Herbert Irschik, Hans Reichenbach, Gerhard Höfle

Journal:

European Journal of Organic Chemistry

Year:

1983

Language:

german

File:

PDF, 588 KB

german, 1983

20

Antibiotika aus Gleitenden Bakterien, XXII. Die Biosynthese des Antibiotikums Myxopyronin A aus Myxococcus fulvus Stamm Mx f50

Werner Kohl, Herbert Irschik, Hans Reichenbach, Gerhard Höfle

Journal:

European Journal of Organic Chemistry

Year:

1984

Language:

german

File:

PDF, 306 KB

german, 1984

21

Antibiotika aus Gleitenden Bakterien, XXIV. Corallopyronin A, B und C – drei neue Antibiotika aus Corallococcus coralloides Cc c127 (Myxobacterales)

Rolf Jansen, Gerhard Höfle, Herbert Irschik, Hans Reichenbach

Journal:

European Journal of Organic Chemistry

Year:

1985

Language:

german

File:

PDF, 737 KB

german, 1985

22

Antibiotika aus Gleitenden Bakterien, XXXV. Isolierung und Strukturaufklärung der Saframycine Mx 1 und Mx 2, neue antitumor-aktive Antibiotika aus Myxococcus xanthus

Wolfram Trowitzsch-Kienast, Herbert Irschik, Hans Reichenbach, Victor Wray, Gerhard Höfle

Journal:

European Journal of Organic Chemistry

Year:

1988

Language:

german

File:

PDF, 681 KB

german, 1988

23

Antibiotika aus Gleitenden Bakterien, XXXVI. Ein neues Isochinolin-Alkaloid aus Myxococcus xanthus

Wolfram Trowitzsch-Kienast, Herbert Irschik, Victor Wray, Hans Reichenbach, Gerhard Höfle

Journal:

European Journal of Organic Chemistry

Year:

1988

File:

PDF, 208 KB

1988

24

Antibiotika aus Gleitenden Bakterien, XXXVII. Sorangicin A, ein hochwirksames Antibiotikum mit neuartiger Makrolid-Polyether-Struktur aus Sorangium cellulosum, So ce12: Spektroskopische Strukturaufklärung, Kristall- und Lösungsstruktur

Rolf Jansen, Gerhard Höfle, Herbert Irschik, Hans Reichenbach, Dietmar Schomburg, Victor Wray

Journal:

European Journal of Organic Chemistry

Year:

1989

Language:

german

File:

PDF, 961 KB

german, 1989

25

Antibiotika aus Gleitenden Bakterien, XXXVIII. Natürliche Strukturvarianten von Sorangicin A aus Sorangium cellulosum, So ce12

Rolf Jansen, Gerhard Höfle, Herbert Irschik, Hans Reichenbach, Victor Wray

Journal:

European Journal of Organic Chemistry

Year:

1989

Language:

german

File:

PDF, 922 KB

german, 1989

26

Antibiotika aus Gleitenden Bakterien, XXXIX. Biosynthese von Sorangicin A in Sorangium cellulosum, So ce12

Rolf Jansen, Gerhard Höfle, Herbert Irschik, Hans Reichenbach, Victor Wray

Journal:

European Journal of Organic Chemistry

Year:

1989

Language:

german

File:

PDF, 374 KB

german, 1989

27

Antibiotics from gliding bacteria, XLII. Chemical modification of sorangicin A and structure — Activity relationship I: Carboxyl and hydroxyl group derivatives

Rolf Jansen, Dietmar Schummer, Herbert Irschik, Gerhard Höfle

Journal:

European Journal of Organic Chemistry

Year:

1990

Language:

english

File:

PDF, 1.65 MB

english, 1990

28

Antibiotika aus Gleitenden Bakterien, L – Chemische Modifikation von Sorangicin A und Struktur-Wirkungs-Beziehung II: Derivate aus Reduktions-, Oxidations- und Umlagerungsreaktionen

Dietmar Schummer, Herbert Irschik, Gerhard Höfle

Journal:

European Journal of Organic Chemistry

Year:

1993

File:

PDF, 1.31 MB

1993

29

Antibiotics from gliding bacteria, LVII. Tartrolons: New boron-containing macrodiolides from Sorangium cellulosum

Dietmar Schummer, Herbert Irschik, Hans Reichenbach, Gerhard Höfle

Journal:

European Journal of Organic Chemistry

Year:

1994

Language:

english

File:

PDF, 637 KB

english, 1994

30

Antibiotics from Gliding Bacteria, LIX. Disorazoles, Highly Cytotoxic Metabolites from the Sorangicin-Producing Bacterium Sorangium Cellulosum, Strain So ce12

Rolf Jansen, Herbert Irschik, Hans Reichenbach, Victor Wray, Gerhard Höfle

Journal:

European Journal of Organic Chemistry

Year:

1994

Language:

english

File:

PDF, 1.52 MB

english, 1994

31

Antibiotics from gliding bacteria, LXIV. Isolation and structure elucidation of sorangiolides A and B, novel macrocyclic lactone carboxylic acids from Sorangium cellulosum

Rolf Jansen, Herbert Irschik, Holger Meyer, Hans Reichenbach, Victor Wray, Dietmar Schomburg, Gerhard Höfle

Journal:

European Journal of Organic Chemistry

Year:

1995

Language:

english

File:

PDF, 596 KB

english, 1995

32

Antibiotics from Gliding Bacteria, LXXIII Indole and Quinoline Derivatives as Metabolites of Tryptophan in Myxobacteria

Bettina Böhlendorf, Norbert Bedorf, Rolf Jansen, Wolfram Trowitzsch-Kienast, Gerhard Höfle, Edgar Forche, Klaus Gerth, Herbert Irschik, Brigitte Kunze, Hans Reichenbach

Journal:

European Journal of Organic Chemistry

Year:

1996

Language:

english

File:

PDF, 524 KB

english, 1996

33

Antibiotics from Gliding Bacteria, LXXV. Absolute Configuration and Biosynthesis of Tartrolon B, a Boron-Containing Macrodiolide from Sorangium cellulosum

Dietmar Schummer, Dietmar Schomburg, Herbert Irschik, Hans Reichenbach, Gerhard Höfle

Journal:

European Journal of Organic Chemistry

Year:

1996

Language:

english

File:

PDF, 421 KB

english, 1996

34

Antibiotics from Gliding Bacteria, LXXVIII. Ripostatin A, B, and C: Isolation and Structure and Structure Elucidation of Novel Metabolites from Sorangium cellulosum

Hermann Augustiniak, Gerhard Höfle, Herbert Irschik, Hans Reichenbach

Journal:

European Journal of Organic Chemistry

Year:

1996

Language:

english

File:

PDF, 657 KB

english, 1996

35

Antibiotics from Gliding Bacteria, LXXX. Chivosazoles A–F: Novel Antifungal and Cytotoxic Macrolides from Sorangium cellulosum (myxobacteria)

Rolf Jansen, Herbert Irschik, Hans Reichenbach, Gerhard Höfle

Journal:

European Journal of Organic Chemistry

Year:

1997

Language:

english

File:

PDF, 859 KB

english, 1997

36

Design, synthesis and biological evaluation of simplified analogues of the RNA polymerase inhibitor etnangien

Dirk Menche, Pengfei Li, Herbert Irschik

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 337 KB

english, 2010

37

Biosynthesis of Thuggacins in Myxobacteria: Comparative Cluster Analysis Reveals Basis for Natural Product Structural Diversity

Kathrin Buntin, Herbert Irschik, Kira J. Weissman, Eva Luxenburger, Helmut Blöcker, Rolf Müller

Journal:

Chemistry & Biology

Year:

2010

Language:

english

File:

PDF, 850 KB

english, 2010

38

Isolation and spectroscopic structure elucidation of sorangicin a, a new type of macrolide-polyether antibiotic from gliding bacteria - XXX.

Rolf Jansen, Victor Wray, Herbert Irschik, Hans Reichenbach, Gerhard Höfle

Journal:

Tetrahedron Letters

Year:

1985

Language:

english

File:

PDF, 260 KB

english, 1985

39

An unusual pattern of carbohydrate utilization inCorallococcus (Myxococcus) coralloides(Myxobacterales)

Herbert Irschik, Hans Reichenbach

Journal:

Archives of Microbiology

Year:

1985

Language:

english

File:

PDF, 619 KB

english, 1985

40

The Thuggacins, Novel Antibacterial Macrolides from Sorangium cellulosum Acting against Selected Gram-positive Bacteria

Irschik, Herbert, Reichenbach, Hans, Höfle, Gerhard, Jansen, Rolf

Journal:

The Journal of Antibiotics

Year:

2007

Language:

english

File:

PDF, 160 KB

english, 2007

41

Structural, functional, and genetic analysis of sorangicin inhibition of bacterial RNA polymerase

Campbell, Elizabeth A, Pavlova, Olga, Zenkin, Nikolay, Leon, Fred, Irschik, Herbert, Jansen, Rolf, Severinov, Konstantin, Darst, Seth A

Journal:

The EMBO Journal

Year:

2005

Language:

english

File:

PDF, 279 KB

english, 2005

42

Isolierung und Totalsynthese der Icumazole und Noricumazole – antimykotische Antibiotika und Kationenkanalblocker aus Sorangium cellulosum

Jenny Barbier, Dr. Rolf Jansen, Dr. Herbert Irschik, Dr. Stefan Benson, Dr. Klaus Gerth, Bettina Böhlendorf, Prof. Dr. Gerhard Höfle, Prof. Dr. Hans Reichenbach, Jens Wegner, Dr. Carsten Zeilinger, Pr

Journal:

Angewandte Chemie

Year:

2012

Language:

german

File:

PDF, 423 KB

german, 2012

43

Berichtigung: Isolierung und Totalsynthese der Icumazole und Noricumazole – antimykotische Antibiotika und Kationenkanalblocker aus Sorangium cellulosum

Jenny Barbier, Dr. Rolf Jansen, Dr. Herbert Irschik, Dr. Stefan Benson, Dr. Klaus Gerth, Bettina Böhlendorf, Prof. Dr. Gerhard Höfle, Prof. Dr. Hans Reichenbach, Jens Wegner, Dr. Carsten Zeilinger, Pr

Journal:

Angewandte Chemie

Year:

2012

File:

PDF, 189 KB

2012

44

Corrigendum: Isolation and Total Synthesis of Icumazoles and Noricumazoles—Antifungal Antibiotics and Cation-Channel Blockers from Sorangium cellulosum

Jenny Barbier, Dr. Rolf Jansen, Dr. Herbert Irschik, Dr. Stefan Benson, Dr. Klaus Gerth, Bettina Böhlendorf, Prof. Dr. Gerhard Höfle, Prof. Dr. Hans Reichenbach, Jens Wegner, Dr. Carsten Zeilinger, Pr

Journal:

Angewandte Chemie International Edition

Year:

2012

File:

PDF, 144 KB

2012

45

Sulfangolids, Macrolide Sulfate Esters from Sorangium cellulosum

Dr. Wiebke Zander, Dr. Herbert Irschik, Dr. Hermann Augustiniak, Dr. Martina Herrmann, Dr. Rolf Jansen, Dipl.-Ing. Heinrich Steinmetz, Dr. Klaus Gerth, Dipl.-Ing. Wolfgang Kessler, Prof. Dr. Markus Ka

Journal:

Chemistry - A European Journal

Year:

2012

Language:

english

File:

PDF, 398 KB

english, 2012

46

Myxobacteria: a source of new antibiotics

Hans Reichenbach, Klaus Gerth, Herbert Irschik, Brigitte Kunze, Gerhard Höfle

Journal:

Trends in Biotechnology

Year:

1988

Language:

english

File:

PDF, 2.35 MB

english, 1988

47

Hepatitis C virus complete life cycle screen for identification of small molecules with pro- or antiviral activity

Juliane Gentzsch, Bettina Hinkelmann, Lars Kaderali, Herbert Irschik, Rolf Jansen, Florenz Sasse, Ronald Frank, Thomas Pietschmann

Journal:

Antiviral Research

Year:

2011

Language:

english

File:

PDF, 1.92 MB

english, 2011

48

Damage ofStreptococcus mutansbiofilms by carolacton, a secondary metabolite from the myxobacteriumSorangium cellulosum

Brigitte Kunze, Michael Reck, Andreas Dötsch, André Lemme, Dietmar Schummer, Herbert Irschik, Heinrich Steinmetz, Irene Wagner-Döbler

Journal:

BMC Microbiology

Year:

2010

Language:

english

File:

PDF, 1.84 MB

english, 2010

49

Intracellular location of flexirubins in Flexibacter elegans (cytophagales)

Herbert Irschik, Hans Reichenbach

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

1978

Language:

english

File:

PDF, 1.24 MB

english, 1978

50

Design, synthesis and biological evaluation of simplified side chains of the macrolide antibiotic etnangien

Mario Altendorfer, Herbert Irschik, Dirk Menche

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 535 KB

english, 2012

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